NPHS2 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
Western blot analysis of rat kidney tissue lysate with NPHS2 polyclonal antibody (Cat # PAB14847).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NPHS2.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human NPHS2.
Host
Rabbit
Theoretical MW (kDa)
42, 34
Reactivity
Human, Mouse, Rat
Specificity
Different from the mouse sequence by one aminoacid.
Form
Lyophilized
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of rat kidney tissue lysate with NPHS2 polyclonal antibody (Cat # PAB14847). -
Gene Info — NPHS2
Entrez GeneID
7827Gene Name
NPHS2
Gene Alias
PDCN, SRN1
Gene Description
nephrosis 2, idiopathic, steroid-resistant (podocin)
Gene Ontology
HyperlinkGene Summary
This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000033186|podocin
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Interactome
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Disease
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