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Last updated: 2016/11/27

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NPHS2 polyclonal antibody

  • Catalog # : PAB14847
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of NPHS2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at internal region of human NPHS2.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 42, 34
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • Different from the mouse sequence by one aminoacid.
  • Form:
  • Lyophilized
  • Purification:
  • Affinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of rat kidney tissue lysate with NPHS2 polyclonal antibody (Cat # PAB14847).
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7827
  • Gene Name:
  • NPHS2
  • Gene Alias:
  • PDCN,SRN1
  • Gene Description:
  • nephrosis 2, idiopathic, steroid-resistant (podocin)
  • Gene Summary:
  • This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000033186,podocin
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