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Last updated: 2016/10/23
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RRM1 polyclonal antibody

  • Catalog # : PAB14831
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of RRM1.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human RRM1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • Epitope: C-terminus.
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity purification
  • Concentration:
  • Lot specific
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) of human placenta stained with RRM1 polyclonal antibody (Cat # PAB14831).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 6240
  • Gene Name:
  • RRM1
  • Gene Alias:
  • R1,RIR1,RR1
  • Gene Description:
  • ribonucleotide reductase M1
  • Gene Summary:
  • This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells. It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region. [provided by RefSeq
  • Other Designations:
  • ribonucleoside-diphosphate reductase M1 chain,ribonucleotide reductase M1 polypeptide,ribonucleotide reductase, R1 subunit,ribonucleotide reductase, large subunit
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