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Last updated: 2020/8/2
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APOE polyclonal antibody (FITC) 

  • Catalog # : PAB14771
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against native APOE.
  • Immunogen:
  • Human Apolipoprotein E.
  • Host:
  • Goat
  • Reactivity:
  • Human
  • Specificity:
  • This antibody specifically binds to human APOE. Molar F/P ratio is 4.6.
  • Form:
  • Lyophilized
  • Conjugation:
  • FITC
  • Purification:
  • This antibody purified by human apo E-Sepharose affinity column and labeled with FITC.
  • Recommend Usage:
  • Immunofluorescence
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 75 mM PBS, 75 mM NaCl, 0.5 mM EDTA, pH 7.4 (0.02% sodium azide, 5 mg/mL BSA).
  • Storage Instruction:
  • Store freeze-dried product at 4°C until opened. After opening, restore to 0.5 mL with distilled water. If it is not completely clear after standing for 1-2 hours at room temperature, centrifuge the product. It is stable for several weeks at 4°C as an undiluted liquid. Do not use for more than one day after dilution. The products are light sensitive and should be keep in dark. To avoid repeated freezing and thawing after reconstitution, we suggest aliquots and storage at -20°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunofluorescence
  • Application Image
  • Immunofluorescence
  • Gene Information
  • Entrez GeneID:
  • 348
  • Gene Name:
  • APOE
  • Gene Alias:
  • AD2,LPG,MGC1571,apoprotein
  • Gene Description:
  • apolipoprotein E
  • Gene Summary:
  • Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq
  • Other Designations:
  • apolipoprotein E3
  • Gene Pathway
  • Related Disease
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