Gabbr1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of Gabbr1.
Immunogen
A synthetic peptide (conjugated with THG) corresponding to amino acids 100-124 of mouse Gabb1.
Host
Rabbit
Theoretical MW (kDa)
130
Reactivity
Mouse, Rat
Specificity
This antibody recognizes N-terminus of mouse gamma-aminobutyric acid (GABA) B receptor 1a. GB1a apparent MW ~130 KDa.
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunocytochemistry
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Gene Info — Gabbr1
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Publication Reference
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No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits.
Kniazeff J, Galvez T, Labesse G, Pin JP.
Journal of Neuroscience 2002 Sep; 22(17):7352.
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Function of GB1 and GB2 subunits in G protein coupling of GABA(B) receptors.
Margeta-Mitrovic M, Jan YN, Jan LY.
PNAS 2001 Nov; 98(25):14649.
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Ligand-induced signal transduction within heterodimeric GABA(B) receptor.
Margeta-Mitrovic M, Jan YN, Jan LY.
PNAS 2001 Dec; 98(25):14643.
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No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits.
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