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SLC31A1 polyclonal antibody

  • Catalog # : PAB14558
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of SLC31A1.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human SLC31A1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Pig, Rat, Xenopus, Zebra fish
  • Form:
  • Liquid
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:250)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris-citrate/phosphate buffer, pH 7-8 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Panel A : Human SLC31A1 staining of human breast cancer tissue. Panel B : Human SLC31A1 antigen competition in human breast cancer tissue.
  • Immunocytochemistry
  • Immunocytochemistry
  • Staining of SLC31A1 overexpressing cell line with SLC31A1 polyclonal antibody (Cat # PAB14558). Panel B is antibody plus peptide competition staining.
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1317
  • Gene Name:
  • SLC31A1
  • Gene Alias:
  • COPT1,CTR1,MGC75487,hCTR1
  • Gene Description:
  • solute carrier family 31 (copper transporters), member 1
  • Gene Summary:
  • Copper is an element essential for life, but excessive copper can be toxic or even lethal to the cell. Therefore, cells have developed sophisticated ways to maintain a critical copper balance, with the intake, export, and intracellular compartmentalization or buffering of copper strictly regulated. The 2 related genes ATP7A (MIM 300011) and ATP7B (MIM 606882), responsible for the human diseases Menkes syndrome (MIM 309400) and Wilson disease (MIM 277900), respectively, are involved in copper export. In S. cerevisiae, the copper uptake genes CTR1, CTR2, and CTR3 have been identified, and in human the CTR1 and CTR2 (MIM 603088) genes have been identified.[supplied by OMIM
  • Other Designations:
  • OTTHUMP00000021950,copper transport 1 homolog,copper transporter 1
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