IKBKAP polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant IKBKAP.
Immunogen
Recombinant protein corresponding to C-terminus of human IKBKAP.
Host
Rabbit
Reactivity
Human
Specificity
Reacts with the C terminus of IKAP.
Form
Liquid
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of IKBKAP in interleukin-1-stimulated 293 cells with IKBKAP polyclonal antibody (Cat # PAB14546) at a 1 : 500 dilution. -
Gene Info — IKBKAP
Entrez GeneID
8518Gene Name
IKBKAP
Gene Alias
DKFZp781H1425, DYS, ELP1, FD, FLJ12497, IKAP, IKI3, TOT1
Gene Description
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. [provided by RefSeq
Other Designations
OTTHUMP00000021869|OTTHUMP00000063889
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Interactome
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Disease
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Publication Reference
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Signal transduction. Docking IkappaB kinases.
Scheidereit C.
Nature 1998 Sep; 395(6699):225.
Application:WB-Ce, WB-Tr, Human, Mammalian cells.
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Signal transduction. Docking IkappaB kinases.
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