LYZ polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against native LYZ.
Immunogen
Native purified human LYZ.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
Immunohistochemistry (Frozen sections) (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (1% BSA, 0.05% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Immunocytochemistry
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Gene Info — LYZ
Entrez GeneID
4069Gene Name
LYZ
Gene Alias
LZM
Gene Description
lysozyme (renal amyloidosis)
Gene Ontology
HyperlinkGene Summary
This gene encodes human lysozyme, whose natural substrate is the bacterial cell wall peptidoglycan (cleaving the beta[1-4]glycosidic linkages between N-acetylmuramic acid and N-acetylglucosamine). Lysozyme is one of the anti-microbial agents found in human milk, and is also present in spleen, lung, kidney, white blood cells, plasma, saliva, and tears. Missense mutations in LYZ have been identified in heritable renal amyloidosis. [provided by RefSeq
Other Designations
1,4-beta-N-acetylmuramidase C|lysozyme|lysozyme C
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Interactome
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Disease
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Publication Reference
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Nuclear factor-kappaB activation in neonatal mouse lung protects against lipopolysaccharide-induced inflammation.
Alvira CM, Abate A, Yang G, Dennery PA, Rabinovitch M.
American Journal of Respiratory and Critical Care Medicine 2007 Apr; 175(8):805.
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Granulomonocyte-associated lysosomal protein expression during in vitro expansion and differentiation of CD34+ hematopoietic progenitor cells.
Scheinecker C, Strobl H, Fritsch G, Csmarits B, Krieger O, Majdic O, Knapp W.
Blood 1995 Dec; 86(11):4115.
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Kupffer cells in multiple organ failure--their activation as revealed by immunohistochemistry for lysozyme, alpha 1-antichymotrypsin, and lectins.
Niki T, Oka T, Shiga J, Machinami R.
Gen Diagn Pathol 1995 May; 141(1):21.
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Nuclear factor-kappaB activation in neonatal mouse lung protects against lipopolysaccharide-induced inflammation.
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