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Last updated: 2016/12/4
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PSMB10 polyclonal antibody

  • Catalog # : PAB14399
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of PSMB10.
  • Immunogen:
  • A synthetic peptide corresponding to human PSMB10.
  • Sequence:
  • C-PTEPVKRSGRYH
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 28.9
  • Reactivity:
  • Human
  • Specificity:
  • Approx 26 KDa band observed in human, liver, lung and lymph node lysates (calculated MW of 28.9 KDa according to NP_002792.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:8000)
    Western Blot (0.3-1 ug/mL).)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • PSMB10 polyclonal antibody (Cat # PAB14399) (0.3 ug/mL) staining of human lung lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5699
  • Gene Name:
  • PSMB10
  • Gene Alias:
  • LMP10,MECL1,MGC1665,beta2i
  • Gene Description:
  • proteasome (prosome, macropain) subunit, beta type, 10
  • Gene Summary:
  • The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. [provided by RefSeq
  • Other Designations:
  • macropain subunit MECl-1,multicatalytic endopeptidase complex subunit MECl-1,proteasome MECl-1,proteasome beta 10 subunit,proteasome catalytic subunit 2i,proteasome subunit MECL1,proteasome subunit beta 7i
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