COL3A1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against native COL3A1.
Immunogen
Native human COL3A1.
Host
Goat
Reactivity
Human
Specificity
Reacts with conformational determinants on human type III collagen as demonstrated by ELISA. May react with type III collagen from other species. Exhibits <10% cross reactivity with collagen type I, II, IV, V, VI. This antibody has not been tested for reactivity with other ECM proteins (e.g., laminin, fibronectin).
Form
Liquid
Isotype
IgG
Recommend Usage
Immunocytochemistry (1:10-1:20)
Immunohistochemistry (1:10-1:20)
The optimal working dilution should be determined by the end user.Storage Buffer
In 100 mM BBS, pH 8.2
Storage Instruction
Store at 4°C.
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Applications
Western Blot
Immunohistochemistry (Frozen sections)
Immunocytochemistry
Enzyme-linked Immunoabsorbent Assay
Dot Blot
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Gene Info — COL3A1
Entrez GeneID
1281Gene Name
COL3A1
Gene Alias
EDS4A, FLJ34534
Gene Description
collagen, type III, alpha 1
Gene Ontology
HyperlinkGene Summary
This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish
Other Designations
Ehlers-Danlos syndrome type IV, autosomal dominant|alpha1 (III) collagen|collagen type III alpha 1|collagen, fetal
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Interactome
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Pathway
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Disease
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