NTF3 polyclonal antibody
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Specification
Product Description
Sheep polyclonal antibody raised against synthetic peptide of NTF3.
Immunogen
A synthetic peptide (conjugated with BSA) corresponding to human, mouse and rat NTF3/Ntf3.
Sequence
YAEHKSHRGEY
Host
Sheep
Reactivity
Chicken, Human, Mouse, Rat
Specificity
A cross reactivity of less than 0.1% to mouse NGF, recombinant human BDNF and NT4/5 has been shown by dot blot.
Form
Lyophilized
Recommend Usage
Western Blot (1-10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS
Storage Instruction
Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry
Enzyme-linked Immunoabsorbent Assay
Dot Blot
Inhibition Assay
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Gene Info — NTF3
Entrez GeneID
4908Gene Name
NTF3
Gene Alias
HDNF, MGC129711, NGF-2, NGF2, NT3
Gene Description
neurotrophin 3
Omim ID
162660Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse. [provided by RefSeq
Other Designations
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Gene Info — Ntf3
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Gene Info — Ntf3
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Interactome
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Pathway
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Disease
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Publication Reference
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Endogenous nerve growth factor and neurotrophin-3 act simultaneously to ensure the survival of postnatal sympathetic neurons in vivo.
Tafreshi AP, Zhou XF, Rush RA.
Neuroscience 1998 Mar; 83(2):373.
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Functional roles of neurotrophin 3 in the developing and mature sympathetic nervous system.
Zhou XF, Rush RA.
Molecular Neurobiology 1996 Dec; 13(3):185.
Application:IHC, Rat, Rat internal carotid nerves.
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Endogenous nerve growth factor and neurotrophin-3 act simultaneously to ensure the survival of postnatal sympathetic neurons in vivo.
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