NRTN polyclonal antibody
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More Files
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Immunohistochemistry (Frozen sections)
Intense NTN-like immunostaining localized to the intestinal crypt and villus epithelium and muscle layers, cryo-sections of tissues fixed by Zamboni's fixative. Immunohistochemical detection of NRTN using NRTN polyclonal antibody (Cat # PAB14338) at a 1 : 2000 dilution.
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Specification
Product Description
Sheep polyclonal antibody raised against recombinant NRTN.
Immunogen
Recombinant protein corresponding to human NRTN.
Host
Sheep
Reactivity
Human, Mouse, Rat
Specificity
Dot blot shows no cross reactivity to GDNF.
Form
Lyophilized
Recommend Usage
Immunohistochemistry (1:2000-1:3000)
Western Blot (1:2000-1:3000)
ELISA (1:2000-1:4000)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS
Storage Instruction
Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Frozen sections)
Intense NTN-like immunostaining localized to the intestinal crypt and villus epithelium and muscle layers, cryo-sections of tissues fixed by Zamboni's fixative. Immunohistochemical detection of NRTN using NRTN polyclonal antibody (Cat # PAB14338) at a 1 : 2000 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NRTN
Entrez GeneID
4902Gene Name
NRTN
Gene Alias
NTN
Gene Description
neurturin
Gene Ontology
HyperlinkGene Summary
Neurturin is a member of the TGF-beta subfamily, TRN. This gene signals through RET and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease. [provided by RefSeq
Other Designations
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Interactome
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Disease
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Publication Reference
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Distribution of neurturin mRNA and immunoreactivity in the peripheral tissues of adult rats.
Xian CJ, Huang BR, Zhou XF.
Brain Research 1999 Jul; 835(2):247.
Application：IHC-Fr, WB-Re, Rat, Kidney, Recombinant protein, Skeletal muscle, Small intestine, Spleen, Submandibular salivary gland.
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Expression of neurturin, GDNF, and their receptors in the adult mouse CNS.
Golden JP, Baloh RH, Kotzbauer PT, Lampe PA, Osborne PA, Milbrandt J, Johnson EM Jr.
The Journal of Comparative Neurology 1998 Aug; 398(1):139.
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Neurturin, a relative of glial-cell-line-derived neurotrophic factor.
Kotzbauer PT, Lampe PA, Heuckeroth RO, Golden JP, Creedon DJ, Johnson EM Jr, Milbrandt J.
Nature 1996 Dec; 384(6608):467.
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Distribution of neurturin mRNA and immunoreactivity in the peripheral tissues of adult rats.
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