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Last updated: 2017/2/19
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AP1B1 polyclonal antibody

  • Catalog # : PAB14335
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of AP1B1.
  • Immunogen:
  • A synthetic peptide (conjugated with diphtheria toxoid) corresponding to amino acids 11-29 of human AP1B1.
  • Sequence:
  • KKGEIFELKAELNSDKKEK
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Rat
  • Specificity:
  • This antibody has been shown to be specific to AP-1 complex subunit beta-1.
  • Form:
  • Lyophilized
  • Recommend Usage:
  • Immunohistochemistry (1:1000-1:5000)
    Western Blot (1:100-1:10000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from PBS
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.
    After reconstitution with deionized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis on human brain lysate under reducing conditions using AP1B1 polyclonal antibody (Cat # PAB14335) at a dilution of 1 : 100. This antibody labels a major protein of approximately 100 KDa of molecular weight and several minor proteins around 70 KDa in both rat and human tissue. The presence of the two lower bands (IgG fragments) is due to the magnetic bead purification method employed.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Frozen sections)
  • Gene Information
  • Entrez GeneID:
  • 162
  • Protein Accession#:
  • Q10567;O35643;P52303;Q2KJB2
  • Gene Name:
  • AP1B1
  • Gene Alias:
  • ADTB1,AP105A,BAM22,CLAPB2
  • Gene Description:
  • adaptor-related protein complex 1, beta 1 subunit
  • Gene Summary:
  • Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Two transcript variants encoding different isoforms have been found for this gene, and variants utilizing alternative polyadenylation signals exist. [provided by RefSeq
  • Other Designations:
  • Golgi adaptor HA1/AP1 adaptin beta subunit,adaptor protein complex AP-1 beta 1 subunit,adaptor-related protein complex 1 beta 1 subunit,beta-adaptin 1,beta-prime-adaptin,clathrin assembly protein complex 1 beta large chain,plasma membrane adaptor HA2/AP2
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