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Last updated: 2017/4/23
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SQSTM1 polyclonal antibody

  • Catalog # : PAB14333
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of SQSTM1.
  • Immunogen:
  • A synthetic peptide (conjugated with blue carrier protein) corresponding to amino acids 424-436 of human SQSTM1.
  • Sequence:
  • IGAALDTIQYSKH
  • Host:
  • Rabbit
  • Reactivity:
  • Bovine, Human, Mouse, Rat
  • Specificity:
  • The specificity was confirmed by immunohistochemical analysis on paraffin embedded human brain.
  • Form:
  • Lyophilized
  • Recommend Usage:
  • Immunohistochemistry (1:500-1:5000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from PBS
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.
    After reconstitution with deionized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Gene Information
  • Entrez GeneID:
  • 8878
  • Gene Name:
  • SQSTM1
  • Gene Alias:
  • A170,OSIL,PDB3,ZIP3,p60,p62,p62B
  • Gene Description:
  • sequestosome 1
  • Gene Summary:
  • This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq
  • Other Designations:
  • EBI3-associated protein p60,Paget disease of bone 3,oxidative stress induced like,phosphotyrosine independent ligand for the Lck SH2 domain p62,ubiquitin-binding protein p62
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