Influenza A (H3N2) M1 polyclonal antibody (FITC)
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Specification
Product Description
Goat polyclonal antibody raised against Influenza A, Phillipines (H3N2).
Immunogen
Influenza A, Phillipines (H3N2).
Host
Goat
Reactivity
Viruses
Specificity
Influenza A matrix protein (M1). Recognizes the M1 protein for any strain of Influenza A. Conservation of the matrix protein sequence between hemagglutinin/Neuraminidase typed strains. Does not react with the M2 matrix protein. Does not react with HEp-2 cells by indirect immunofluorescence. Does not react with Influenza B, Adenovirus, Respiratory syncytial virus and Parainfluenza viruses (1-3).
Form
Liquid
Conjugation
FITC
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 10 mM PBS, pH 7.2 (10 mg/mL BSA, 0.09% sodium azide)
Storage Instruction
Store in the dark at 4°C. For long term storage store at -20°C.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunofluorescence
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Publication Reference
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Inhibition of influenza virus matrix (M1) protein expression and virus replication by U6 promoter-driven and lentivirus-mediated delivery of siRNA.
Hui EK, Yap EM, An DS, Chen IS, Nayak DP.
The Journal of General Virology 2004 Jul; 85(Pt 7):1877.
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Conserved cysteine and histidine residues in the putative zinc finger motif of the influenza A virus M1 protein are not critical for influenza virus replication.
Hui EK, Ralston K, Judd AK, Nayak DP.
The Journal of General Virology 2003 Nov; 84(Pt 11):3105.
Application:IF, Dog, MDCK cells .
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Basic residues of the helix six domain of influenza virus M1 involved in nuclear translocation of M1 can be replaced by PTAP and YPDL late assembly domain motifs.
Hui EK, Barman S, Yang TY, Nayak DP.
Journal of Virology 2003 Jun; 77(12):7078.
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Inhibition of influenza virus matrix (M1) protein expression and virus replication by U6 promoter-driven and lentivirus-mediated delivery of siRNA.
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