Rabbit polyclonal antibody raised against synthetic peptide of AGT.
A synthetic peptide corresponding to mouse and human AGT.
The rabbit anti-human/mouse Angiotensin II antibody detects specifically target derived from recombinant protein at various concentrations. Cross reactivity with mouse and rat are expected from sequence similarity.
ELISA (1:100000) Enzyme Immunoassay (2.62 ng/mL) The optimal working dilution should be determined by the end user.
Lyophilized from PBS
Store at -20°C. For long term storage store at -80°C. Aliquot after reconstitution to avoid repeated freezing and thawing.
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq