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Last updated: 2016/10/23
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MARCKS polyclonal antibody

  • Catalog # : PAB14167
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against recombinant MARCKS.
  • Immunogen:
  • Recombinant protein corresponding to human MARCKS.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 80
  • Reactivity:
  • Human, Mammals
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:10000)
    Immunofluorescence (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum (5 mM sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot of whole rat cortex (Lane 1), cerebellum (Lane 2), brain stem (Lane 3) and spinal cord (Lane 4) homogenate stained with MARCKS polyclonal antibody (Cat # PAB14167), at dilution of 1 : 10,000.
    A prominent band running with an apparent SDS-PAGE molecular weight of ~ 80 KDa corresponds to MARCKS.
  • Immunohistochemistry
  • Immunofluorescence
  • Immunofluorescence
  • View of mixed neuron/glial cultures stained with MARCKS polyclonal antibody (Cat # PAB14167) (red) and Chicken MAP2 polyclonal antibody.
    Note that the MARCKS antibody stains vesicular structures both in the glial cells and in the dendrites of the neurons, which are strongly stained with the MAP2 antibody.
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry
  • Gene Information
  • Entrez GeneID:
  • 4082
  • Gene Name:
  • Gene Alias:
  • Gene Description:
  • myristoylated alanine-rich protein kinase C substrate
  • Gene Summary:
  • The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000017045,myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L),phosphomyristin
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