TSPAN8 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of TSPAN8.
Immunogen
A synthetic peptide corresponding to human TSPAN8.
Sequence
QRPCQSYNGKQVYKE
Host
Goat
Theoretical MW (kDa)
26
Reactivity
Human
Specificity
Approx 24 KDa band observed in human colon lysates (calculated MW of 26.0 KDa according to NP_004607.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:16000)
Western Blot (0.01-0.03 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
TSPAN8 polyclonal antibody (Cat # PAB14142) (0.01 ug/mL) staining of human colon lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TSPAN8
Entrez GeneID
7103Protein Accession#
NP_004607.1Gene Name
TSPAN8
Gene Alias
CO-029, TM4SF3
Gene Description
tetraspanin 8
Omim ID
600769Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expressed in different carcinomas. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq
Other Designations
transmembrane 4 superfamily member 3|tumor-associated antigen CO-029
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Interactome
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Disease
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Publication Reference
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Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.
Grarup N, Andersen G, Krarup NT, Albrechtsen A, Schmitz O, Jorgensen T, Borch-Johnsen K, Hansen T, Pedersen O.
Diabetes 2008 Sep; 57(9):2534.
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Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.
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