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Last updated: 2017/3/26

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SSRP1 polyclonal antibody

  • Catalog # : PAB14118
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against partial recombinant SSRP1.
  • Immunogen:
  • Recombinant GST fusion protein corresponding to N-terminus of human SSRP1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.05% sodium azide, 0.05% proclin 300)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot was performed using nuclear extracts from HeLa cells (HeLa NE, 20 ug) and the SSRP1 polyclonal antibody (Cat # PAB14118) at dilution 1 : 1,000 in TBS-Tween + 5% skimmed milk.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6749
  • Gene Name:
  • SSRP1
  • Gene Alias:
  • FACT,FACT80,T160
  • Gene Description:
  • structure specific recognition protein 1
  • Gene Summary:
  • The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq
  • Other Designations:
  • chromatin-specific transcription elongation factor 80 kDa subunit,cisplatin-DNA SSRP,facilitates chromatin remodeling 80 kDa subunit,high mobility group box,recombination signal sequence recognition protein
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