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Last updated: 2016/10/23
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JMJD2C polyclonal antibody

  • Catalog # : PAB14072
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of JMJD2C.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to internal region of human JMJD2C.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Recommend Usage:
  • ELISA (1:50)
    Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In serum (0.05% sodium azide)
  • Storage Instruction:
  • Store at -20°C. For long term storage store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Nuclear extracts of HeLa cells (40 ug) were analysed by Western blot using JMJD2B polyclonal antibody (Cat # PAB14072) diluted 1 : 1,000 in TBS-Tween containing 5% skimmed milk.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • JMJD2C
  • Gene Alias:
  • FLJ25949,GASC1,JHDM3C,KDM4C,KIAA0780,bA146B14.1
  • Gene Description:
  • jumonji domain containing 2C
  • Gene Summary:
  • This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • JmjC domain-containing histone demethylation protein 3C,OTTHUMP00000021052,OTTHUMP00000044461,gene amplified in squamous cell carcinoma 1
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