NPPB polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of NPPB.
Immunogen
A synthetic peptide (conjugated with bovine thyroglobulin) corresponding to human NPPB.
Host
Rabbit
Reactivity
Human, Rat
Specificity
Specific for human and rat Brain Natriuretic Peptide (BNP).
Form
Lyophilized
Recommend Usage
Immunofluorescence (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized antiserum
Storage Instruction
Store at 4°C on dry atmosphere.
After reconstitution with 0.1 mL PBS containing 10 mg/mL BSA, store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry
Immunofluorescence
Enzyme-linked Immunoabsorbent Assay
Radioimmunoassay
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Gene Info — NPPB
Entrez GeneID
4879Gene Name
NPPB
Gene Alias
BNP
Gene Description
natriuretic peptide precursor B
Omim ID
600295Gene Ontology
HyperlinkGene Summary
This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis. [provided by RefSeq
Other Designations
OTTHUMP00000002506|OTTHUMP00000044486|brain type natriuretic peptide|natriuretic protein
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