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Last updated: 2016/12/4
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C4A/C4B polyclonal antibody

  • Catalog # : PAB13926
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against C4A/C4B.
  • Immunogen:
  • Purified human C4A/C4B.
  • Host:
  • Goat
  • Reactivity:
  • Human
  • Specificity:
  • Monospecific by immunoelectrophoresis when tested against pooled human plasma and 2X concentrated pooled human serum.
  • Form:
  • Liquid
  • Recommend Usage:
  • The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In TBS, pH 7.4 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 720
  • Gene Name:
  • C4A
  • Gene Alias:
  • C4,C4A2,C4A3,C4A4,C4A6,C4S,CO4,CPAMD2,MGC164979,RG
  • Gene Description:
  • complement component 4A (Rodgers blood group)
  • Gene Summary:
  • This gene encodes the acidic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus and type I diabetes mellitus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. [provided by RefSeq
  • Other Designations:
  • C4A anaphylatoxin,OTTHUMP00000029266,Rodgers form of C4,acidic C4,complement component 4A
  • Gene Information
  • Entrez GeneID:
  • 721
  • Gene Name:
  • C4B
  • Gene Alias:
  • C4A,C4A13,C4A91,C4B1,C4B12,C4B2,C4B3,C4B5,C4F,CH,CO4,CPAMD3,FLJ60561,MGC164979
  • Gene Description:
  • complement component 4B (Chido blood group)
  • Gene Summary:
  • This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. [provided by RefSeq
  • Other Designations:
  • Chido form of C4,OTTHUMP00000029269,basic C4,complement C4B1a,complement component 4B,complement component 4B (Childo blood group)
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