PAK2 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of PAK2 expression in (a) A-431 and (B) NIH/3T3 cell lysates in the absence or (C) presence of blocking peptide with PAK2 polyclonal antibody (Cat # PAB13807) at 1 ug/mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of PAK2 in human lung tissue with PAK2 polyclonal antibody (Cat # PAB13807) at 1 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PAK2.
Immunogen
A synthetic peptide corresponding to N-terminus of human PAK2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
Recognizes p53R2.
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
Immunohistochemistry (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of PAK2 expression in (a) A-431 and (B) NIH/3T3 cell lysates in the absence or (C) presence of blocking peptide with PAK2 polyclonal antibody (Cat # PAB13807) at 1 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of PAK2 in human lung tissue with PAK2 polyclonal antibody (Cat # PAB13807) at 1 ug/mL . -
Gene Info — PAK2
Entrez GeneID
5062GeneBank Accession#
NP_002568Gene Name
PAK2
Gene Alias
PAK65, PAKgamma
Gene Description
p21 protein (Cdc42/Rac)-activated kinase 2
Omim ID
605022Gene Ontology
HyperlinkGene Summary
The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq
Other Designations
S6/H4 kinase|p21 (CDKN1A)-activated kinase 2|p21-activated kinase 2
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Interactome
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