CRADD polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Detection of endogenous CRADD (human) in HEK293T cells by CRADD polyclonal antibody (Cat # PAB13793) at 1 : 1000 dilution. Total cell extracts (50 ug) were run on a SDS-gel followed by incubation with HRP-coupled anti-rabbit secondary antibody.
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Specification
Product Description
Rabbit polyclonal antibody raised against full length recombinant CRADD.
Immunogen
Recombinant N-terminus tag fusion protein corresponding to full length human CRADD.
Host
Rabbit
Reactivity
Human
Specificity
Recognizes RAIDD.
Form
Liquid
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In buffer containing 0.02% sodium azide
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Detection of endogenous CRADD (human) in HEK293T cells by CRADD polyclonal antibody (Cat # PAB13793) at 1 : 1000 dilution. Total cell extracts (50 ug) were run on a SDS-gel followed by incubation with HRP-coupled anti-rabbit secondary antibody.Immunoprecipitation
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Gene Info — CRADD
Entrez GeneID
8738Gene Name
CRADD
Gene Alias
MGC9163, RAIDD
Gene Description
CASP2 and RIPK1 domain containing adaptor with death domain
Omim ID
603454Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins. [provided by RefSeq
Other Designations
RIP-associated ICH1/CED3-homologous protein with death domain|RIP-associated protein with a death domain|caspase and RIP adaptor with death domain|death adaptor molecule RAIDD|death domain containing protein CRADD
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Interactome
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Disease
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