CRNN polyclonal antibody
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More Files
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Immunofluorescence
Immunodetection of human CRNN using CRNN polyclonal antibody (Cat # PAB13784) at 1 : 100 dilution.
Staining performed on frozen sections of esophagus (A, B), foreskin (C, D) and scalp (E, F).
Cornulin is expressed in the outer most layer of scalp skin and in the inner root sheat of the hair follicle, in normal esophagus, the staining is localized in the upper spinous and granular layers with strong peripheral localization.
Control sections (B, D, F) show no staining.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CRNN.
Immunogen
A synthetic peptide corresponding to amino acids 259-274 of human CRNN.
Sequence
EATNDQNRGTETHGQG
Host
Rabbit
Reactivity
Human
Specificity
Recognizes human cornulin. Detects a band of ~70 KDa by Western blot.
Form
Liquid
Recommend Usage
Western Blot (1:2000)
Immunohistochemistry (1:100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.01% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry
Immunofluorescence
Immunodetection of human CRNN using CRNN polyclonal antibody (Cat # PAB13784) at 1 : 100 dilution.
Staining performed on frozen sections of esophagus (A, B), foreskin (C, D) and scalp (E, F).
Cornulin is expressed in the outer most layer of scalp skin and in the inner root sheat of the hair follicle, in normal esophagus, the staining is localized in the upper spinous and granular layers with strong peripheral localization.
Control sections (B, D, F) show no staining. -
Gene Info — CRNN
Entrez GeneID
49860Gene Name
CRNN
Gene Alias
C1orf10, DRC1, PDRC1, SEP53
Gene Description
cornulin
Omim ID
611312Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the "fused gene" family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation. [provided by RefSeq
Other Designations
53 kDa squamous epithelial-induced stress protein|OTTHUMP00000014323|squamous epithelial heat shock protein 53|tumor-related protein
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Interactome
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Disease
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