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Last updated: 2016/11/27
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CRNN polyclonal antibody

  • Catalog # : PAB13784
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CRNN.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 259-274 of human CRNN.
  • Sequence:
  • EATNDQNRGTETHGQG
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • Recognizes human cornulin. Detects a band of ~70 KDa by Western blot.
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:2000)
    Immunohistochemistry (1:100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.01% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunofluorescence
  • Immunofluorescence
  • Immunodetection of human CRNN using CRNN polyclonal antibody (Cat # PAB13784) at 1 : 100 dilution.
    Staining performed on frozen sections of esophagus (A, B), foreskin (C, D) and scalp (E, F).
    Cornulin is expressed in the outer most layer of scalp skin and in the inner root sheat of the hair follicle, in normal esophagus, the staining is localized in the upper spinous and granular layers with strong peripheral localization.
    Control sections (B, D, F) show no staining.
  • Application Image
  • Western Blot
  • Immunohistochemistry
  • Gene Information
  • Gene Name:
  • CRNN
  • Gene Alias:
  • C1orf10,DRC1,PDRC1,SEP53
  • Gene Description:
  • cornulin
  • Gene Summary:
  • This gene encodes a member of the "fused gene" family of proteins, which contain N-terminus EF-hand domains and multiple tandem peptide repeats. The encoded protein contains two EF-hand Ca2+ binding domains in its N-terminus and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. This gene, also known as squamous epithelial heat shock protein 53, may play a role in the mucosal/epithelial immune response and epidermal differentiation. [provided by RefSeq
  • Other Designations:
  • 53 kDa squamous epithelial-induced stress protein,OTTHUMP00000014323,squamous epithelial heat shock protein 53,tumor-related protein
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