STAT2 polyclonal antibody
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More Files
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Western Blot (Cell lysate)
HeLa cell extract was resolved by electrophoresis, transferred to nitrocellulose, and probed with STAT2 polyclonal antibody (Cat # PAB13772).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of STAT2.
Immunogen
A synthetic peptide corresponding to C-terminus of human STAT2.
Host
Rabbit
Reactivity
Human
Specificity
Recognizes STAT2.
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.2 (0.2% gelatin, 0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
HeLa cell extract was resolved by electrophoresis, transferred to nitrocellulose, and probed with STAT2 polyclonal antibody (Cat # PAB13772).Immunohistochemistry
Immunoprecipitation
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Gene Info — STAT2
Entrez GeneID
6773Gene Name
STAT2
Gene Alias
ISGF-3, MGC59816, P113, STAT113
Gene Description
signal transducer and activator of transcription 2, 113kDa
Omim ID
600556Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. In response to interferon (IFN), this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G), in which this protein acts as a transactivator, but lacks the ability to bind DNA directly. Transcription adaptor P300/CBP (EP300/CREBBP) has been shown to interact specifically with this protein, which is thought to be involved in the process of blocking IFN-alpha response by adenovirus. [provided by RefSeq
Other Designations
interferon alpha induced transcriptional activator|signal transducer and activator of transcription 2
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Interactome
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Pathway
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Disease
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