PSPH polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
PSPH polyclonal antibody (Cat # PAB13675) (0.05 ug/mL) staining of mouse brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PSPH.
Immunogen
A synthetic peptide corresponding to human PSPH.
Sequence
C-RQQVKDNAKWYITD
Host
Goat
Theoretical MW (kDa)
25
Reactivity
Human, Mouse
Specificity
Approximately 26 KDa band observed in human brain (hippocampus) and in mouse brain lysates (calculated MW of 25.0 KDa according to human NP_004568.2 and 25.1KDa according to mouse NP_598661.1).
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:32000)
Western Blot (0.05-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
PSPH polyclonal antibody (Cat # PAB13675) (0.05 ug/mL) staining of mouse brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PSPH
Entrez GeneID
5723Protein Accession#
NP_004568.2Gene Name
PSPH
Gene Alias
PSP
Gene Description
phosphoserine phosphatase
Omim ID
172480Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. [provided by RefSeq
Other Designations
L-3-phosphoserine phosphatase|O-phosphoserine phosphohydrolase|OTTHUMP00000025059|PSPase
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Interactome
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Pathway
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Publication Reference
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Phosphoserine phosphatase of human brain: partial purification, characterization, regional distribution, and effect of certain modulators including psychoactive drugs.
Veeranna, Shetty KT.
Neurochemical Research 1990 Dec; 15(12):1203.
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Phosphoserine phosphatase of human brain: partial purification, characterization, regional distribution, and effect of certain modulators including psychoactive drugs.
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