SCARB2 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
SCARB2 polyclonal antibody (Cat # PAB13673) (0.1 ug/mL) staining of human cerebral cortex lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
SCARB2 polyclonal antibody (Cat # PAB13673) (3.8 ug/mL) staining of paraffin embedded human cerebral cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
-
Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of SCARB2.
Immunogen
A synthetic peptide corresponding to amino acids at internal region of human SCARB2.
Sequence
C-NKANIQFGDNGTTIS
Host
Goat
Theoretical MW (kDa)
54.3
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Concentration
0.5 mg/mL
Recommend Usage
ELISA (1:4000)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
SCARB2 polyclonal antibody (Cat # PAB13673) (0.1 ug/mL) staining of human cerebral cortex lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
SCARB2 polyclonal antibody (Cat # PAB13673) (3.8 ug/mL) staining of paraffin embedded human cerebral cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — SCARB2
Entrez GeneID
950Protein Accession#
NP_005497.1Gene Name
SCARB2
Gene Alias
AMRF, CD36L2, HLGP85, LIMPII, SR-BII
Gene Description
scavenger receptor class B, member 2
Omim ID
602257Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Studies of the similar protein in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. Deficiency of the similar protein in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. [provided by RefSeq
Other Designations
85 kDa lysosomal sialoglycoprotein scavenger receptor class B, member 2|CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II)|lysosomal integral membrane protein II
-
Interactome
-
Pathway
-
Disease
-
Publication Reference
-
Establishment of cell lines with increased susceptibility to EV71/CA16 by stable overexpression of SCARB2.
Li X, Fan P, Jin J, Su W, An D, Xu L, Sun S, Zhang Y, Meng X, Gao F, Kong W, Jiang C.
Virology Journal 2013 Aug; 10:250.
Application：Flow Cyt, WB-Tr, Human, Monkey, HEK 293, RD, Vero cells.
-
Array-based gene discovery with three unrelated subjects shows SCARB2/LIMP-2 deficiency causes myoclonus epilepsy and glomerulosclerosis.
Berkovic SF, Dibbens LM, Oshlack A, Silver JD, Katerelos M, Vears DF, Lullmann-Rauch R, Blanz J, Zhang KW, Stankovich J, Kalnins RM, Dowling JP, Andermann E, Andermann F, Faldini E.
American Journal of Human Genetics 2008 Feb; 82(3):673.
-
Establishment of cell lines with increased susceptibility to EV71/CA16 by stable overexpression of SCARB2.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com