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Last updated: 2016/12/4
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GCKR polyclonal antibody

  • Catalog # : PAB13669
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of GCKR.
  • Immunogen:
  • A synthetic peptide corresponding to human GCKR.
  • Sequence:
  • KRFQHVIETPEPGK-C
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 68.7
  • Reactivity:
  • Mouse, Rat
  • Specificity:
  • Approximately 70 KDa band observed in mouse and rat liver lysates (calculated MW of 68.7 KDa according to human NP_001477.1 and of 68.9 KDa according to rat NP_037252.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:8000)
    Western Blot (0.1-0.3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • GCKR polyclonal antibody (Cat # PAB13669) (0.1 ug/mL) staining of rat liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2646
  • Gene Name:
  • GCKR
  • Gene Alias:
  • GKRP
  • Gene Description:
  • glucokinase (hexokinase 4) regulator
  • Gene Summary:
  • This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY). [provided by RefSeq
  • Other Designations:
  • glucokinase (hexokinase 4) regulatory protein,glucokinase regulator,glucokinase regulatory protein,hexokinase 4
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