Rabbit polyclonal antibody raised against synthetic peptide of PRKCE.
A synthetic peptide (conjugated with KLH) corresponding to amino acids 721-737 of human PRKCE.
Human, Mouse, Rat
These rabbit polyclonal antibodies are made against specific peptide regions of the PKC epsilon protein. By using specific peptides for the PKC delta that has effectively minimized cross reactivity between the various isoforms. These antibodies are useful in the screening of PKC epsilon proteins in various biological tissues and tumorigenesis studies.
Western Blot (1:1000) The optimal working dilution should be determined by the end user.
In PBS (0.05% sodium azide)
Store at 4°C. For long term storage store at -80°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq