PTGES/PTGES2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PTGES/PTGES2.
Immunogen
A synthetic peptide corresponding to human PTGES/PTGES2.
Host
Rabbit
Reactivity
Human
Specificity
This antibody is specific to microsomal human PGE Synthase (PGE Isomerase or mPGEi).
Form
Liquid
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In DPBS
Storage Instruction
Store at -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Transfected lysate)
Lane V= vector-transfected HCT-116 cells.
Lane P= PGES-transfected HCT-116 cells. -
Gene Info — PTGES
Entrez GeneID
9536Gene Name
PTGES
Gene Alias
MGC10317, MGST-IV, MGST1-L1, MGST1L1, MPGES, PGES, PIG12, PP102, PP1294, TP53I12, mPGES-1
Gene Description
prostaglandin E synthase
Omim ID
605172Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq
Other Designations
MGST1-like 1|OTTHUMP00000022345|glutathione S-transferase 1-like 1|microsomal glutathione S-transferase 1-like 1|microsomal prostaglandin E synthase-1|p53-induced apoptosis protein 12|p53-induced gene 12|tumor protein p53 inducible protein 12
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Gene Info — PTGES2
Entrez GeneID
80142Gene Name
PTGES2
Gene Alias
C9orf15, FLJ14038, GBF1, MGC11289, PGES2, mPGES-2
Gene Description
prostaglandin E synthase 2
Omim ID
608152Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq
Other Designations
GATE-binding factor 1|OTTHUMP00000022231|gamma-interferon-activated transcriptional element-binding factor 1|membrane-associated prostaglandin E synthase 2|microsomal prostaglandin E synthase-2
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Interactome
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Pathway
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Disease
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