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Last updated: 2016/12/4
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PTGES/PTGES2 polyclonal antibody

  • Catalog # : PAB13620
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of PTGES/PTGES2.
  • Immunogen:
  • A synthetic peptide corresponding to human PTGES/PTGES2.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is specific to microsomal human PGE Synthase (PGE Isomerase or mPGEi).
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In DPBS
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Lane V= vector-transfected HCT-116 cells.
    Lane P= PGES-transfected HCT-116 cells.
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 9536
  • Gene Name:
  • PTGES
  • Gene Alias:
  • MGC10317,MGST-IV,MGST1-L1,MGST1L1,MPGES,PGES,PIG12,PP102,PP1294,TP53I12,mPGES-1
  • Gene Description:
  • prostaglandin E synthase
  • Gene Summary:
  • The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq
  • Other Designations:
  • MGST1-like 1,OTTHUMP00000022345,glutathione S-transferase 1-like 1,microsomal glutathione S-transferase 1-like 1,microsomal prostaglandin E synthase-1,p53-induced apoptosis protein 12,p53-induced gene 12,tumor protein p53 inducible protein 12
  • Gene Information
  • Gene Name:
  • PTGES2
  • Gene Alias:
  • C9orf15,FLJ14038,GBF1,MGC11289,PGES2,mPGES-2
  • Gene Description:
  • prostaglandin E synthase 2
  • Gene Summary:
  • The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq
  • Other Designations:
  • GATE-binding factor 1,OTTHUMP00000022231,gamma-interferon-activated transcriptional element-binding factor 1,membrane-associated prostaglandin E synthase 2,microsomal prostaglandin E synthase-2
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