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Last updated: 2016/12/4
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CYP3A4 polyclonal antibody

  • Catalog # : PAB13615
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CYP3A4.
  • Immunogen:
  • A synthetic peptide corresponding to human CYP3A4.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:2000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In TBS
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Western Blot
  • Lane 1 : molecular weight markers.
    Lane 2 : CYP3A4 -100 ng.
    Lane 3 : CYP3A4-300 ng.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 1576
  • Gene Name:
  • CYP3A4
  • Gene Alias:
  • CP33,CP34,CYP3A,CYP3A3,HLP,MGC126680,NF-25,P450C3,P450PCN1
  • Gene Description:
  • cytochrome P450, family 3, subfamily A, polypeptide 4
  • Gene Summary:
  • This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. [provided by RefSeq
  • Other Designations:
  • P450-III, steroid inducible,cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3,cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4,cytochrome P450, subfamily IIIA, polypeptide 4,glucocorticoid-inducible P450,nifedipine o
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