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Last updated: 2017/8/20
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GSTM1 polyclonal antibody

  • Catalog # : PAB13602
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against recombinant GSTM1.
  • Immunogen:
  • Recombinant protein corresponding to human GSTM1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Rat
  • Specificity:
  • This antibody reacts specifically with GSTs of the mu class and does not cross react with alpha or pi class GSTs.
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In unpurified antiserum
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 2944
  • Gene Name:
  • GSTM1
  • Gene Alias:
  • GST1,GSTM1-1,GSTM1a-1a,GSTM1b-1b,GTH4,GTM1,H-B,MGC26563,MU,MU-1
  • Gene Description:
  • glutathione S-transferase mu 1
  • Gene Summary:
  • Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq
  • Other Designations:
  • GST class-mu 1,HB subunit 4,OTTHUMP00000013346,OTTHUMP00000013347,S-(hydroxyalkyl)glutathione lyase,glutathione S-alkyltransferase,glutathione S-aralkyltransferase,glutathione S-aryltransferase,glutathione S-transferase M1
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