IBSP polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against native IBSP.
Immunogen
Native purified IBSP from human bone sialoprotein.
Host
Rabbit
Reactivity
Human, Rat
Specificity
Recognizes human and rat bone sialoprotein. Does not cross-react with human osteopontin or osteonectin.
Form
Lyophilized
Recommend Usage
Immunocytochemistry (1:100)
The optimal working dilution should be determined by the end user.Storage Instruction
Store at 4°C on dry atmosphere.
After reconstitution with distilled water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunocytochemistry
Enzyme-linked Immunoabsorbent Assay
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Gene Info — IBSP
Entrez GeneID
3381Gene Name
IBSP
Gene Alias
BNSP, BSP, BSP-II, SP-II
Gene Description
integrin-binding sialoprotein
Omim ID
147563Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a major structural protein of the bone matrix. It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types, including hypertrophic chondrocytes, osteoblasts, osteocytes, and osteoclasts. The only extraskeletal site of its synthesis is the trophoblast. This protein binds to calcium and hydroxyapatite via its acidic amino acid clusters, and mediates cell attachment through an RGD sequence that recognizes the vitronectin receptor. [provided by RefSeq
Other Designations
bone sialoprotein II
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Interactome
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Pathway
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Disease
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