COL2A1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against native COL2A1.
Immunogen
Native purified COL2A1 from fetal chicken cartilage.
Host
Rabbit
Reactivity
Chicken
Specificity
This antibody reacts with chicken collagen type II 100%, no crossreactivity with chicken collagen type I and III, no crossreactivity with human, mouse and rat collagen type II.
Form
Lyophilized
Purification
Affinity purification
Recommend Usage
Immunohistochemistry (1:200-1:600)
Immunofluorescence (1:40)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS.
Storage Instruction
Store lyophilized product at 4°C on dry atmosphere. For prolonged storage prepare appropriate aliquots and store at or below -20°C.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunofluorescence
Enzyme-linked Immunoabsorbent Assay
Radioimmunoassay
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Gene Info — COL2A1
Entrez GeneID
395069Gene Name
COL2A1
Gene Alias
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Gene Description
collagen, type II, alpha 1
Gene Ontology
HyperlinkGene Summary
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Other Designations
alpha 1 type II procollagen|alpha 1 type IIA collagen|collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital)|procollagen alpha 1(II)
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Publication Reference
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Small molecule inhibitors of WNT/beta-catenin signaling block IL1beta/TNFalpha induced cartilage degradation.
Landman EB, Miclea RL, van Blitterswijk CA, Karperien M.
Arthritis Research & Therapy 2013 Aug; 15:R19.
Application：IHC, Mouse, Mouse bones.
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Small molecule inhibitors of WNT/beta-catenin signaling block IL1beta/TNFalpha induced cartilage degradation.
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