COL2A1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against native COL2A1.
Immunogen
Native purified COL2A1 from human cartilage.
Host
Rabbit
Reactivity
Human
Specificity
This antibody reacts with human collagen type II, cross-reactivity with human collagen type I, and IV <1.0%, human collagens type III, V, IX and XI <0.1%, human fibronectin <0.1%.
Form
Lyophilized
Recommend Usage
Immunohistochemistry (1:200-1:600)
Immunofluorescence (1:80)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS
Storage Instruction
Store at -20°C.
Aliquot after reconstitution to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunofluorescence
Enzyme-linked Immunoabsorbent Assay
Radioimmunoassay
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Gene Info — COL2A1
Entrez GeneID
1280Gene Name
COL2A1
Gene Alias
ANFH, AOM, COL11A3, MGC131516, SEDC
Gene Description
collagen, type II, alpha 1
Gene Ontology
HyperlinkGene Summary
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000195063|cartilage collagen|chondrocalcin|collagen II, alpha-1 polypeptide
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Interactome
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