SLC35D1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of SLC35D1 in A-20 lysate with SLC35D1 polyclonal antibody (Cat # PAB13384) at (A) 1 and (B) 2 ug/mL .
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SLC35D1.
Immunogen
Recombinant protein corresponding to N-terminus 14 amino acids of human SLC35D1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Cell lysate)
Western blot analysis of SLC35D1 in A-20 lysate with SLC35D1 polyclonal antibody (Cat # PAB13384) at (A) 1 and (B) 2 ug/mL . -
Gene Info — SLC35D1
Entrez GeneID
23169Protein Accession#
NP_055954Gene Name
SLC35D1
Gene Alias
KIAA0260, MGC138236, UGTREL7
Gene Description
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
Omim ID
610804Gene Ontology
HyperlinkGene Summary
Glycosylation of cellular glycoconjugates occurs in the endoplasmic reticulum (ER) and Golgi compartment, and requires transport of nucleotide sugars from the cytosol into the lumen of the ER and Golgi by specific transporters. The protein encoded by this gene resides in the ER, and transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to the ER lumen. It may participate in glucuronidation and/or chondroitin sulfate biosynthesis. Mutations in this gene are associated with Schneckenbecken dysplasia
Other Designations
OTTHUMP00000010965|UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter
-
Interactome
-
Disease
-
Publication Reference
-
Nucleotide-sugar transporter SLC35D1 is critical to chondroitin sulfate synthesis in cartilage and skeletal development in mouse and human.
Hiraoka S, Furuichi T, Nishimura G, Shibata S, Yanagishita M, Rimoin DL, Superti-Furga A, Nikkels PG, Ogawa M, Katsuyama K, Toyoda H, Kinoshita-Toyoda A, Ishida N, Isono K, Sanai Y, Cohn DH, Koseki H, Ikegawa S.
Nature Medicine 2007 Nov; 13(11):1363.
Application：IF, WB, Hamster, Yeast, CHO-K1 cells, Microsomes.
-
Molecular physiology and pathology of the nucleotide sugar transporter family (SLC35).
Ishida N, Kawakita M.
Pflugers Archiv 2004 Feb; 447(5):768.
Application：WB, Human, Cancers, Mammalian cells.
-
Molecular characterization of human UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter, a novel nucleotide sugar transporter with dual substrate specificity.
Muraoka M, Kawakita M, Ishida N.
FEBS Letters 2001 Apr; 495(1-2):87.
Application：IF, Mouse, CHO-K1 cells.
-
Nucleotide-sugar transporter SLC35D1 is critical to chondroitin sulfate synthesis in cartilage and skeletal development in mouse and human.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com