TNPO3 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TNPO3.
Immunogen
A synthetic peptide corresponding to N-terminus 18 amino acids of human TNPO3.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of TNPO3 in Raji cell lysate with TNPO3 polyclonal antibody (Cat # PAB13371) at (A) 1 and (B) 2 ug/mL . -
Gene Info — TNPO3
Entrez GeneID
23534Protein Accession#
EAW83708Gene Name
TNPO3
Gene Alias
IPO12, MTR10A, TRN-SR, TRN-SR2, TRNSR
Gene Description
transportin 3
Omim ID
610032Gene Ontology
HyperlinkGene Summary
TNPO3 is a nuclear import receptor for serine/arginine-rich (SR) proteins, which are essential precursor-mRNA splicing factors (Kataoka et al., 1999 [PubMed 10366588]).[supplied by OMIM
Other Designations
importin 12|transportin-SR
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Interactome
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Disease
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Publication Reference
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Identification of host proteins required for HIV infection through a functional genomic screen.
Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman A, Xavier RJ, Lieberman J, Elledge SJ.
Science 2008 Jan; 319(5865):921.
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A human importin-beta family protein, transportin-SR2, interacts with the phosphorylated RS domain of SR proteins.
Lai MC, Lin RI, Huang SY, Tsai CW, Tarn WY.
The Journal of Biological Chemistry 2000 Mar; 275(11):950.
Application:IF, WB-Tr, Human, HeLa cells.
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Transportin-SR, a nuclear import receptor for SR proteins.
Kataoka N, Bachorik JL, Dreyfuss G.
The Journal of Cell Biology 1999 Jun; 145(6):1145.
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Identification of host proteins required for HIV infection through a functional genomic screen.
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