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Last updated: 2016/11/27
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SIRT2 polyclonal antibody

  • Catalog # : PAB13340
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of SIRT2.
  • Immunogen:
  • A synthetic peptide corresponding to N-terminus 17 amino acids of human SIRT2.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (2.5-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of SIRT2 in human brain tissue lysate with SIRT2 polyclonal antibody (Cat # PAB13340) at (A) 2.5 and (B) 5 ug/mL .
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of human brain tissue using SIRT2 polyclonal antibody (Cat # PAB13340) at 2.5 ug/mL .
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Gene Name:
  • SIRT2
  • Gene Alias:
  • SIR2,SIR2L,SIR2L2
  • Gene Description:
  • sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae)
  • Gene Summary:
  • This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two transcript variants result from alternative splicing of this gene. [provided by RefSeq
  • Other Designations:
  • silencing information regulator 2-like,silent information regulator 2,sir2-related protein type 2,sirtuin 2,sirtuin type 2
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