SLITRK3 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SLITRK3.
Immunogen
A synthetic peptide corresponding to C-terminus 14 amino acids of human SLITRK3.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of SLITRK3 in SK-N-SH cell lysate with SLITRK3 polyclonal antibody (Cat # PAB13332) at (A) 0.5 and (B) 1 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of SLITRK3 in human brain tissue with SLITRK3 polyclonal antibody (Cat # PAB13332) at 2.5 ug/mL . -
Gene Info — SLITRK3
Entrez GeneID
22865Protein Accession#
O94933Gene Name
SLITRK3
Gene Alias
KIAA0848, MGC138681
Gene Description
SLIT and NTRK-like family, member 3
Omim ID
609679Gene Ontology
HyperlinkGene Summary
Members of the SLITRK family, such as SLITRK3, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK3, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]).[supplied by OMIM
Other Designations
slit and trk like 3 protein|slit and trk like gene 3
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Interactome
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Publication Reference
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Human SLITRK family genes: genomic organization and expression profiling in normal brain and brain tumor tissue.
Aruga J, Yokota N, Mikoshiba K.
Gene 2003 Oct; 315:87.
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Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth.
Aruga J, Mikoshiba K.
Molecular and Cellular Neurosciences 2003 Sep; 24(1):117.
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Human SLITRK family genes: genomic organization and expression profiling in normal brain and brain tumor tissue.
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