FEZ2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FEZ2.
Immunogen
A synthetic peptide corresponding to internal region 15 amino acids of human FEZ2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of FEZ2 in NIH/3T3 cell lysate with FEZ2 polyclonal antibody (Cat # PAB13316) at (A) 0.5, and (B) 1 ug/mL .Immunofluorescence
Immunofluorescence of human brain tissue using FEZ2 polyclonal antibody (Cat # PAB13316) at 5 ug/mL . -
Gene Info — FEZ2
Entrez GeneID
9637Protein Accession#
NP_001036013Gene Name
FEZ2
Gene Alias
HUM3CL, MGC117372
Gene Description
fasciculation and elongation protein zeta 2 (zygin II)
Omim ID
604826Gene Ontology
HyperlinkGene Summary
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Other orthologs include the rat gene that encodes zygin II, which can bind to synaptotagmin. [provided by RefSeq
Other Designations
pre-T/NK cell associated protein (3Cl)|zygin 2
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Interactome
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Disease
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Publication Reference
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FEZ1 dimerization and interaction with transcription regulatory proteins involves its coiled-coil region.
Assmann EM, Alborghetti MR, Camargo ME, Kobarg J.
The Journal of Biological Chemistry 2006 Apr; 281(15):9869.
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Identification of a tissue-non-specific homologue of axonal fasciculation and elongation protein zeta-1.
Fujita T, Ikuta J, Hamada J, Okajima T, Tatematsu K, Tanizawa K, Kuroda S.
Biochemical and Biophysical Research Communications 2004 Jan; 313(3):738.
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Mammalian homologue of the Caenorhabditis elegans UNC-76 protein involved in axonal outgrowth is a protein kinase C zeta-interacting protein.
Kuroda S, Nakagawa N, Tokunaga C, Tatematsu K, Tanizawa K.
The Journal of Cell Biology 1999 Feb; 144(3):403.
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FEZ1 dimerization and interaction with transcription regulatory proteins involves its coiled-coil region.
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