GRIK4 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of GRIK4 in rat brain tissue lysate with GRIK4 polyclonal antibody (Cat # PAB13313) at (A) 0.5 (B) 1 and (C) 2 ug/mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain tissue using GRIK4 polyclonal antibody (Cat # PAB13313) at 2.5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GRIK4.
Immunogen
A synthetic peptide corresponding to C-terminus 19 amino acids of human GRIK4.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of GRIK4 in rat brain tissue lysate with GRIK4 polyclonal antibody (Cat # PAB13313) at (A) 0.5 (B) 1 and (C) 2 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain tissue using GRIK4 polyclonal antibody (Cat # PAB13313) at 2.5 ug/mL . -
Gene Info — GRIK4
Entrez GeneID
2900Protein Accession#
Q16099Gene Name
GRIK4
Gene Alias
EAA1, GRIK, KA1
Gene Description
glutamate receptor, ionotropic, kainate 4
Omim ID
600282Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that belongs to the glutamate-gated ionic channel family. Glutamate functions as the major excitatory neurotransmitter in the central nervous system through activation of ligand-gated ion channels and G protein-coupled membrane receptors. The protein encoded by this gene forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. [provided by RefSeq
Other Designations
excitatory amino acid receptor 1|glutamate receptor KA1
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Interactome
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Pathway
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Disease
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Publication Reference
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GRIK4 and the kainate receptor.
Mayer ML.
The American Journal of Psychiatry 2007 Aug; 164(8):1148.
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Kainate receptors.
Pinheiro P, Mulle C.
Cell and Tissue Research 2006 Jul; 326(2):457.
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Cytogenetic and genetic evidence supports a role for the kainate-type glutamate receptor gene, GRIK4, in schizophrenia and bipolar disorder.
Pickard BS, Malloy MP, Christoforou A, Thomson PA, Evans KL, Morris SW, Hampson M, Porteous DJ, Blackwood DH, Muir WJ.
Molecular Psychiatry 2006 Sep; 11(9):847.
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GRIK4 and the kainate receptor.
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