FNBP1L polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of FNBP1L in human brain tissue lysate in (A) the absence and (B) the presence of blocking peptide with FNBP1L polyclonal antibody (Cat # PAB13310) at 0.5 ug/mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain tissue using FNBP1L polyclonal antibody (Cat # PAB13310) at 2.5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FNBP1L.
Immunogen
A synthetic peptide corresponding to N-terminus 15 amino acids of human FNBP1L.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of FNBP1L in human brain tissue lysate in (A) the absence and (B) the presence of blocking peptide with FNBP1L polyclonal antibody (Cat # PAB13310) at 0.5 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of human brain tissue using FNBP1L polyclonal antibody (Cat # PAB13310) at 2.5 ug/mL . -
Gene Info — FNBP1L
Entrez GeneID
54874Protein Accession#
NP_001020119Gene Name
FNBP1L
Gene Alias
C1orf39, TOCA1
Gene Description
formin binding protein 1-like
Omim ID
608848Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene binds to both CDC42 and N-WASP. This protein promotes CDC42-induced actin polymerization by activating the N-WASP-WIP complex and, therefore, is involved in a pathway that links cell surface signals to the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
transducer of Cdc42-dependent actin assembly 1
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Interactome
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Disease
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Publication Reference
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Regulation of neuronal morphology by Toca-1, an F-BAR/EFC protein that induces plasma membrane invagination.
Kakimoto T, Katoh H, Negishi M.
The Journal of Biological Chemistry 2006 Sep; 281(39):29042.
Application：IF, WB-Ti, WB-Tr, Humam, Rat, 293T, PC-12 cells, Brain, Kidney, Lung, Heart, Liver, Thymus, Spleen.
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Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex.
Ho HY, Rohatgi R, Lebensohn AM, Le Ma, Li J, Gygi SP, Kirschner MW.
Cell 2004 Jul; 118(2):203.
Application：WB-Ce, WB-Re, Frog, Frog egg extract, Recombinant protein.
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Regulation of neuronal morphology by Toca-1, an F-BAR/EFC protein that induces plasma membrane invagination.
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