RASD2 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of RASD2.
Immunogen
A synthetic peptide corresponding to C-terminus 15 amino acids of human RASD2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of RASD2 in human colon tissue lysate with RASD2 polyclonal antibody (Cat # PAB13305) at (A) 1 and (B) 2 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of RASD2 in human colon tissue with RASD2 polyclonal antibody (Cat # PAB13305) at 2.5 ug/mL . -
Gene Info — RASD2
Entrez GeneID
23551Protein Accession#
Q96D21Gene Name
RASD2
Gene Alias
MGC:4834, Rhes, TEM2
Gene Description
RASD family, member 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a Ras-related protein that enriched in striatum. The product of this gene binds to GTP and possesses intrinsic GTPase activity. The gene belongs to the Ras superfamily of small GTPases. The exact function of this gene is unknown, but most striatum-specific mRNAs characterized to date encode components of signal transduction cascades. [provided by RefSeq
Other Designations
GTP-binding protein Rhes|Ras homolog enriched in striatum|tumor endothelial marker 2
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Disease
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Publication Reference
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Rhes is involved in striatal function.
Spano D, Branchi I, Rosica A, Pirro MT, Riccio A, Mithbaokar P, Affuso A, Arra C, Campolongo P, Terracciano D, Macchia V, Bernal J, Alleva E, Di Lauro R.
Molecular and Cellular Biochemistry 2004 Jul; 24(13):5788.
Application:WB, Human, Mouse, HeLa cells, Mouse brains.
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Thyroid hormone regulation of rhes, a novel Ras homolog gene expressed in the striatum.
Vargiu P, Morte B, Manzano J, Perez J, de Abajo R, Gregor Sutcliffe J, Bernal J.
Brain Res Mol Brain Res 2001 Oct; 94(1-2):1.
Application:IHC-Fr, WB-Ti, Rat, Rat brains.
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Cell surface tumor endothelial markers are conserved in mice and humans.
Carson-Walter EB, Watkins DN, Nanda A, Vogelstein B, Kinzler KW, St Croix B.
Cancer Research 2001 Sep; 61(18):6649.
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Rhes is involved in striatal function.
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