UIMC1 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of UIMC1.
Immunogen
A synthetic peptide corresponding to N-terminus 17 amino acids of human UIMC1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of UIMC1 in 293 cell lysate in (A) the absence and (B) presence of blocking peptide with UIMC1 polyclonal antibody (Cat # PAB13296) at 1 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of UIMC1 in human spleen tissue with UIMC1 polyclonal antibody (Cat # PAB13296) at 2.5 ug/mL . -
Gene Info — UIMC1
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Interactome
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Disease
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Publication Reference
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CCDC98 targets BRCA1 to DNA damage sites.
Liu Z, Wu J, Yu X.
Nature Structural & Molecular Biology 2007 Jul; 14(8):716.
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CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response.
Kim H, Huang J, Chen J.
Nature Structural & Molecular Biology 2007 Aug; 14(8):710.
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Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response.
Wang B, Matsuoka S, Ballif BA, Zhang D, Smogorzewska A, Gygi SP, Elledge SJ.
Science 2007 May; 316(5828):1194.
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CCDC98 targets BRCA1 to DNA damage sites.
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