STEAP1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of STEAP1 in human spleen tissue lysate with STEAP1 polyclonal antibody (Cat # PAB13292) at (A) 1 and (B) 2 ug/mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of STEAP1 in human spleen tissue with STEAP1 polyclonal antibody (Cat # PAB13292) at 2.5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of STEAP1.
Immunogen
A synthetic peptide corresponding to internal region 16 amino acids of human STEAP1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of STEAP1 in human spleen tissue lysate with STEAP1 polyclonal antibody (Cat # PAB13292) at (A) 1 and (B) 2 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of STEAP1 in human spleen tissue with STEAP1 polyclonal antibody (Cat # PAB13292) at 2.5 ug/mL . -
Gene Info — STEAP1
Entrez GeneID
26872Protein Accession#
EAL24166Gene Name
STEAP1
Gene Alias
MGC19484, PRSS24, STEAP
Gene Description
six transmembrane epithelial antigen of the prostate 1
Omim ID
604415Gene Ontology
HyperlinkGene Summary
This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions. [provided by RefSeq
Other Designations
six transmembrane epithelial antigen of the prostate
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Interactome
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Disease
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Publication Reference
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STEAP, a prostate tumor antigen, is a target of human CD8+ T cells.
Alves PM, Faure O, Graff-Dubois S, Cornet S, Bolonakis I, Gross DA, Miconnet I, Chouaib S, Fizazi K, Soria JC, Lemonnier FA, Kosmatopoulos K.
Cancer Immunology, Immunotherapy : CII 2006 Dec; 55(12):1515.
Application：WB-Ce, Human, 1355, DU145, LNCaP, M113, MCF-7 cells.
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Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells.
Ohgami RS, Campagna DR, Greer EL, Antiochos B, McDonald A, Chen J, Sharp JJ, Fujiwara Y, Barker JE, Fleming MD.
Nature Genetics 2005 Oct; 37(11):1264.
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STEAP: a prostate-specific cell-surface antigen highly expressed in human prostate tumors.
Hubert RS, Vivanco I, Chen E, Rastegar S, Leong K, Mitchell SC, Madraswala R, Zhou Y, Kuo J, Raitano AB, Jakobovits A, Saffran DC, Afar DE.
PNAS 1999 Dec; 96(25):14523.
Application：IHC-P, WB-Ce, WB-Ti, WB-Tr, Human, Mouse, 3T3 STEAP, 3T3, LAPC-4 AD, LAPC-9 AD, LAPC-9 AI, Prostate, LNCaP, DU145, PC-3, HeLa, Colo 205, CaCo-2, LoVo, UM-UC-3, TCCSUP, 5637, OV-1063, PA-1, SW 626, BxPC-3, HPAC, Capan-1, RO-ES cells, Bladder, .
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STEAP, a prostate tumor antigen, is a target of human CD8+ T cells.
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