FYB polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of FYB.
Immunogen
A synthetic peptide corresponding to N-terminus 17 amino acids of human FYB.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of FYB in K-562 cell lysate with FYB polyclonal antibody (Cat # PAB13281) at (A) 0.5 and (B) 1 ug/mL .Immunocytochemistry
Immunocytochemistry of FYB in K-562 cells with FYB polyclonal antibody (Cat # PAB13281) at 10 ug/mL . -
Gene Info — FYB
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Interactome
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Disease
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Publication Reference
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Adhesion and degranulation-promoting adapter protein (ADAP) positively regulates T cell sensitivity to antigen and T cell survival.
Mueller KL, Thomas MS, Burbach BJ, Peterson EJ, Shimizu Y.
Journal of Immunology 2007 Sep; 179(6):3559.
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Regulation of NF-kappaB activation in T cells via association of the adapter proteins ADAP and CARMA1.
Medeiros RB, Burbach BJ, Mueller KL, Srivastava R, Moon JJ, Highfill S, Peterson EJ, Shimizu Y.
Science 2007 May; 316(5825):754.
Application:WB-Ce, Mouse, Mouse T cells.
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Positive regulation of T cell activation and integrin adhesion by the adapter Fyb/Slap.
Griffiths EK, Krawczyk C, Kong YY, Raab M, Hyduk SJ, Bouchard D, Chan VS, Kozieradzki I, Oliveira-Dos-Santos AJ, Wakeham A, Ohashi PS, Cybulsky MI, Rudd CE, Penninger JM.
Science 2001 Sep; 293(5538):2260.
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Adhesion and degranulation-promoting adapter protein (ADAP) positively regulates T cell sensitivity to antigen and T cell survival.
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