STMN1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of STMN1 in human brain tissue lysate with STMN1 polyclonal antibody (Cat # PAB13272) at (A) 0.5 and (B) 1 ug/mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of STMN1 in human brain tissue with STMN1 polyclonal antibody (Cat # PAB13272) at 2.5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of STMN1.
Immunogen
A synthetic peptide corresponding to N-terminus 17 amino acids of human STMN1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of STMN1 in human brain tissue lysate with STMN1 polyclonal antibody (Cat # PAB13272) at (A) 0.5 and (B) 1 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of STMN1 in human brain tissue with STMN1 polyclonal antibody (Cat # PAB13272) at 2.5 ug/mL . -
Gene Info — STMN1
Entrez GeneID
3925Protein Accession#
AAH82228Gene Name
STMN1
Gene Alias
LAP18, Lag, OP18, PP17, PP19, PR22, SMN
Gene Description
stathmin 1/oncoprotein 18
Omim ID
151442Gene Ontology
HyperlinkGene Summary
This gene belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. The encoded protein is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000008527|OTTHUMP00000008528|OTTHUMP00000008530|leukemia-associated phosphoprotein p18|metablastin|oncoprotein 18|phosphoprotein 19|prosolin|stathmin 1
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Interactome
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Pathway
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Disease
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Publication Reference
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Role of stathmin in the regulation of the mitotic spindle: potential applications in cancer therapy.
Mistry SJ, Atweh GF.
Mt Sinai J Med 2002 Oct; 69(5):299.
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Stathmin and its phosphoprotein family: general properties, biochemical and functional interaction with tubulin.
Curmi PA, Gavet O, Charbaut E, Ozon S, Lachkar-Colmerauer S, Manceau V, Siavoshian S, Maucuer A, Sobel A.
Cell Structure and Function 1999 Oct; 24(5):345.
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Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules.
Belmont LD, Mitchison TJ.
Cell 1996 Feb; 84(4):623.
Application：IP, WB-Re, Bovine, Frog, Purified proteins, Xenopus eggs.
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Role of stathmin in the regulation of the mitotic spindle: potential applications in cancer therapy.
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