MAPKAP1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of MAPKAP1 in human skeletal muscle tissue lysate with MAPKAP1 polyclonal antibody (Cat # PAB13256) at (A) 0.5, (B) 1 and (C) 2 ug/mL .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of MAPKAP1 in human skeletal muscle tissue with MAPKAP1 polyclonal antibody (Cat # PAB13256) at 2.5 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MAPKAP1.
Immunogen
A synthetic peptide corresponding to N-terminus 19 amino acids of human MAPKAP1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of MAPKAP1 in human skeletal muscle tissue lysate with MAPKAP1 polyclonal antibody (Cat # PAB13256) at (A) 0.5, (B) 1 and (C) 2 ug/mL .Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of MAPKAP1 in human skeletal muscle tissue with MAPKAP1 polyclonal antibody (Cat # PAB13256) at 2.5 ug/mL . -
Gene Info — MAPKAP1
Entrez GeneID
79109Protein Accession#
NP_001006618Gene Name
MAPKAP1
Gene Alias
JC310, MGC2745, MIP1, SIN1, SIN1b, SIN1g
Gene Description
mitogen-activated protein kinase associated protein 1
Omim ID
610558Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene. [provided by RefSeq
Other Designations
MEKK2-interacting protein 1|OTTHUMP00000022139|OTTHUMP00000022140|OTTHUMP00000022141|OTTHUMP00000064207|SAPK-interacting protein 1|ras inhibitor MGC2745|stress-activated map kinase interacting protein 1|stress-activated protein kinase-interacting 1
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Interactome
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Disease
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Publication Reference
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SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.
Jacinto E, Facchinetti V, Liu D, Soto N, Wei S, Jung SY, Huang Q, Qin J, Su B.
Cell 2006 Sep; 127(1):125.
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Mip1, an MEKK2-interacting protein, controls MEKK2 dimerization and activation.
Cheng J, Zhang D, Kim K, Zhao Y, Zhao Y, Su B.
Molecular and Cellular Biology 2005 Jul; 25(14):5955.
Application：WB-Tr, Human, Monkey, COS-1, HEK 293T cells.
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Alternative polyadenylation and splicing of mRNAs transcribed from the human Sin1 gene.
Schroder W, Cloonan N, Bushell G, Sculley T.
Gene 2004 Sep; 339:17.
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SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity.
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