ORAI1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of ORAI1 in human ovary tissue lysate with ORAI1 polyclonal antibody (Cat # PAB13248) at 1 ug/mL in the (A) absence or (B) presence of blocking peptide.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of ORAI1 in human spleen tissue with ORAI1 polyclonal antibody (Cat # PAB13248) at 10 ug/mL .
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ORAI1.
Immunogen
A synthetic peptide corresponding to N-terminus 18 amino acids of human ORAI1.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Recommend Usage
Western Blot (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of ORAI1 in human ovary tissue lysate with ORAI1 polyclonal antibody (Cat # PAB13248) at 1 ug/mL in the (A) absence or (B) presence of blocking peptide.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry of ORAI1 in human spleen tissue with ORAI1 polyclonal antibody (Cat # PAB13248) at 10 ug/mL . -
Gene Info — ORAI1
Entrez GeneID
84876Protein Accession#
Q96D31Gene Name
ORAI1
Gene Alias
CRACM1, FLJ14466, ORAT1, TMEM142A
Gene Description
ORAI calcium release-activated calcium modulator 1
Omim ID
610277Gene Ontology
HyperlinkGene Summary
CRACM1 is a plasma membrane protein essential for store-operated calcium entry (Vig et al., 2006 [PubMed 16645049]).[supplied by OMIM
Other Designations
calcium release-activated calcium channel protein 1|calcium release-activated calcium modulator 1|transmembrane protein 142A
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Interactome
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Publication Reference
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Calcium signals mediated by STIM and Orai proteins--a new paradigm in inter-organelle communication.
Soboloff J, Spassova MA, Dziadek MA, Gill DL.
Biochimica et Biophysica Acta 2006 Nov; 1763(11):1161.
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Coronavirus replication and pathogenesis: Implications for the recent outbreak of severe acute respiratory syndrome (SARS), and the challenge for vaccine development.
Navas-Martin SR, Weiss S.
Journal of Neurovirology 2004 Apr; 10(2):75.
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Calcium signaling mechanisms in T lymphocytes.
Lewis RS.
Annual Review of Immunology 2001 Jan; 19:497.
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Calcium signals mediated by STIM and Orai proteins--a new paradigm in inter-organelle communication.
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