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Last updated: 2017/4/23
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PSENEN polyclonal antibody

  • Catalog # : PAB13229
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of PSENEN.
  • Immunogen:
  • A synthetic peptide corresponding C-terminus to 13 amino acids of human PSENEN.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Form:
  • Liquid
  • Recommend Usage:
  • Western Blot (0.5-1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of PSENEN in K-562 cell lysate with PSENEN polyclonal antibody (Cat # PAB13229) at (A) 0.5, (B) 1, and (C) 2 ug/mL .
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescence of PSENEN in K-562 cells with PSENEN polyclonal antibody (Cat # PAB13229) at 20 ug/mL .
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • PSENEN
  • Gene Alias:
  • MDS033,MSTP064,PEN-2,PEN2
  • Gene Description:
  • presenilin enhancer 2 homolog (C. elegans)
  • Gene Summary:
  • Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase. [provided by RefSeq
  • Other Designations:
  • hematopoietic stem/progenitor cells protein MDS033,presenilin enhancer 2
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